Twenty-five years ago, CSI changed the way that TV viewers and the world looked at forensics.

Created by Anthony Zuiker , CSI turned the focus to using science to solve crimes, and after the premiere aired on October 6, 2000, well, the rest was history. Over its 15-year-run, the cast included William Petersen , Marg Helgenberger , Jorja Fox , George Eads , Gary Dourdan , Paul Guilfoyle , Eric Szmanda , and Robert David Hall, and included quite a few memorable guest stars and episodes.

Below, for the 25th anniversary, TV Insider spoke with Anthony Zuiker about the beginning of CSI, some of its more memorable early episodes, including Quentin Tarantino ‘s “Grave Danger,” and much more.

Congratulations on the 25th anniversary!

Anthony Zuiker: I don’t know where the tim

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