When will Joe Mixon return and play? Will Joe Mixon be back again this season? Read the latest Joe Mixon injury updates and return date for Week 6 (2025).

Houston Texans starting running back Joe Mixon (foot) has been on the non-football injury/reserve list throughout the opening month of the campaign and has yet to make any significant progress.

Given that Mixon has yet to return to the practice field, his status for the remainder of the season is in limbo.

When will Mixon return to action, and what is his fantasy football outlook when he does? Let's dive in. Be sure to check all of our fantasy football rankings for 2025:

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