EAST RUTHERFORD, N.J. − Eagles star cornerback Quinyon Mitchell left the game against the Giants in the second quarter with a hamstring injury.

He was listed as questionable to return, but ruled out in the second half.

It's a big loss for the Eagles as Mitchell was named NFC Defensive Player of the Week after his strong game against the Buccaneers on Sept. 28. Buy Philadelphia Eagles tickets

Adoree Jackson, the former Giant who had lost his starting job to Kelee Ringo, replaced him in the game.

The Eagles suffered another loss in the secondary when Reed Blankenship left with an apparent leg injury while colliding with teammate Cooper DeJean with 4:50 left in the third quarter. There was no word on his injury.

Surprisingly, Marcus Epps replaced Blankenship, and not Sydney Brown,

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