Two of the top teams in the American Conference clash when the 24th-ranked South Florida Bulls meet the North Texas Mean Green on Friday night. USF is coming off a 54-26 win over Charlotte on Oct. 3, while North Texas downed South Alabama 36-22 on Sept. 27. The Bulls (4-1, 1-0 American), who have won two in a row, are 1-1 on the road this season. The Mean Green (5-0, 1-0 American), who have outscored their opponents 224-100, are 3-0 on their home field in 2025.
Kickoff from DATCU Stadium in Denton, Texas, is at 7:30 p.m. ET. South Florida leads the all-time series 2-0. The Mean Green are 1.5-point favorites in the latest South Florida vs. North Texas odds, while the over/under for total points scored is 66.5 via SportsLine consensus. Before making any North Texas vs. South Florida pic