The 14th-ranked Missouri Tigers will get their first true test of the 2025 college football season when they host the No. 8 Alabama Crimson Tide on Saturday. Mizzou (5-0, 1-0 SEC) has yet to face a ranked team and has played just two Power Conference opponents, as the Tigers defeated UMass, 42-6, in their previous game before a bye last week. Meanwhile, Alabama (4-1, 2-0) has looked like a typical Tide team since losing its opener to Florida State. The Tide are coming off back-to-back wins over ranked SEC teams in Vanderbilt and Georgia. Alabama lists star receiver Ryan Williams as probable.

Kickoff is at noon ET from Memorial Stadium in Columbia, Mo. The Crimson Tide are 3.5-point favorites in the latest Missouri vs. Alabama odds, after opening as 6.5-point favorites. The over/under

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