INDIANAPOLIS (AP) — Arizona Cardinals quarterback Kyler Murray will not play Sunday against the Indianapolis Colts after being placed on the inactive list before the game.

Murray has been dealing with an injured foot. He did not practice Wednesday or Thursday and was a limited participant in Friday's lighter workout. Murray had not missed a game since 2023.

With Murray out, longtime veteran Jacoby Brissett will start for the Cardinals (2-3). Brissett started for most of two seasons with the Colts in 2017, when Andrew Luck missed the entire season with a shoulder injury, and in 2019 after Luck's sudden retirement.

Murray was injured in the second half of Arizona's embarrassing 22-21 loss to Tennessee. He missed two plays late in the third quarter while getting treatment, but he returned

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