Fantasy football start em, sit em MNF lineups advice for Bills vs. Falcons on Monday Night Football in Week 6 (2025). NFL matchups analysis and MNF starts/sits.

In Week 6, we have another Monday Night doubleheader, beginning with an NFC vs AFC class between the Bills and Falcons. The Bills are coming off their first loss of the season, while the Falcons had last week off following a big Week 4 win. We're looking at two potential playoff teams here, and many fantasy matchups will be decided in this game.

Below, read about the fantasy football outlooks for key players like James Cook , Keon Coleman , Dalton Kincaid , Kyle Pitts Sr. , Khalil Shakir , Michael Penix Jr. , Josh Allen , and more. Which Bills and Falcons players should you start or sit in Week 6?

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