A private ribbon-cutting ceremony celebrated the opening of Arch Grants’ newly expanded headquarters in Downtown West on Wednesday, marking a new chapter for the nonprofit that’s become a cornerstone of St. Louis’ startup scene. The new space, affectionately dubbed HQ2, is located at 2315 Locust Street and coincided with the announcement of a new pilot lending program in partnership with the James S. McDonnell Foundation.
Thirteen years after launching as a bold idea to attract and retain entrepreneurs in St. Louis, Arch Grants has grown into a major driver of the region’s innovation economy. The organization has funded more than 270 companies and deployed roughly $19 million in non-dilutive grants—free capital with no strings attached—helping founders build businesses that stay and scale