Breast cancer remains the most common cancer among women worldwide. According to the World Health Organization (WHO), in 2024, around 2.4 million women were diagnosed with breast cancer globally, and approximately 685,000 women died from the disease. Despite advances in treatment, not all patients respond to chemotherapy, leaving doctors and patients searching for answers.

To understand why some women respond differently, we spoke to Dr. Mandeep Singh Malhotra, Director of Surgical Oncology at CK Birla Hospital, Delhi. “Chemotherapy works for many, but breast cancer is not one-size-fits-all. Several factors affect how well a patient responds,” he explains.

Tumour type matters

One of the main reasons is tumour heterogeneity. Most breast cancers are hormone-positive, which means they g

See Full Page