The Missouri Lottery offers several draw games for those aiming to win big. Here’s a look at Oct. 21, 2025, results for each game:

Winning Mega Millions numbers from Oct. 21 drawing

02-18-27-34-59, Mega Ball: 18

Check Mega Millions payouts and previous drawings here.

Winning Pick 3 numbers from Oct. 21 drawing

Midday: 5-8-1

Midday Wild: 3

Evening: 4-9-9

Evening Wild: 6

Check Pick 3 payouts and previous drawings here.

Winning Pick 4 numbers from Oct. 21 drawing

Midday: 1-2-1-7

Midday Wild: 3

Evening: 3-2-3-0

Evening Wild: 9

Check Pick 4 payouts and previous drawings here.

Winning Cash4Life numbers from Oct. 21 drawing

05-10-30-45-53, Cash Ball: 03

Check Cash4Life payouts and previous drawings here.

Winning Cash Pop numbers from Oct. 21 drawing

Early Bird: 08

Morning:

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