An accident involving two buses on a highway in Uganda has left at least 63 people dead. Photo: AP PHOTO

A road accident involving two buses on one of Uganda's busiest highways has killed at least 63 people and left others injured.

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The crash happened just after midnight on the highway between the capital Kampala and the northern city of Gulu, police said on Wednesday.

Initial investigations suggest it was caused by two buses coming from opposite directions trying to overtake other vehicles, a truck and an SUV.

"In the process both buses met head-on during the overtaking manoeuvres

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