For the first time, scientists have ranked antidepressants by their physical side effects, revealing significant differences in how these drugs affect weight, blood pressure, and heart rate. The large-scale study, led by researchers at King’s College London’s Institute of Psychiatry, Psychology & Neuroscience (IoPPN) and the University of Oxford, compared 30 commonly prescribed antidepressants across more than 150 clinical trials involving over 58,000 patients. Some antidepressants caused patients to gain up to 2kg in just eight weeks, while others reduced weight or significantly altered heart rate and blood pressure. Experts say the findings could help clinicians better match treatments to individual health needs rather than relying on one-size-fits-all prescribing. The study, publi
Not all antidepressants are equal: Study ranks drugs by side effects; check complete list

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