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San Francisco is on the comeback, which led CNBC to spend a few days to broadcast "Power Lunch" from the network's stunning studios in the city.

Ahead of this special programming, I sought to find the companies based in the city that were making investors the most money this year. Just as the city itself defies expectations, so did this stock search —with some names that may surprise you.

San Francisco is one of the world's great cities. Culture, food, beauty and business power the peninsula. Yes, the city has problems, but finding great stocks to invest in from the area is not one of them, if you know where to look.

Going into this search the Power Lunch team expected most of the stocks would be A.I. rela

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