College football fans circled this matchup in the preseason because it was a game between the No. 2 (PSU) and No. 3 (OSU) teams in the AP poll. Ohio State held up its end of the bargain, but Penn State hasn’t come close to meeting preseason expectations.

The Buckeyes are 7-0 and have won six-straight games by 18 points or more. The Nittany Lions are 3-4 with four consecutive losses. Former head coach James Franklin was fired after Week 7, and PSU has yet to beat a Big Ten team.

A matchup that was pegged as a potential preview for the national championship now lists Ohio State as high as a 19.5-point favorite. Read on to see my Penn State vs. Ohio State best bets, with odds provided by the best Ohio sportsbooks .

RELATED: Take a deeper dive into Ohio State’s Week 10 odds vs. Pe

See Full Page