Look whooo’s gone missing again!

A popular barn owl with a history of wanderlust has once again gone AWOL from a Long Island Nature Center.

Nebula, a 6-year-old captive-bred European barn owl, somehow slipped away from her handler over the weekend, and flew away from the only home she’s ever known — Sweetbriar Nature Center in Smithtown.

It appears falconry equipment used to restrict the owl may have malfunctioned, letting the 1-pound bird with a 35-inch wingspan loose.

The owl relies on humans for her care, according to Isabel Fernandes, Sweetbriar’s wildlife care coordinator. But it is a bird, so there is a slight chance it could adapt.

“She could possibly be catching food on her own, and she might be figuring out life out there — we’re not 100% sure,” Fernandes said. “We need peo

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