The seventh-ranked Ole Miss Rebels look to stay in the SEC championship race when they battle the South Carolina Gamecocks in a key matchup on Saturday. The Gamecocks are coming off a 29-22 loss to Alabama, while Ole Miss downed Oklahoma 34-26 on Oct. 25. The Gamecocks (3-5, 1-5 SEC), who are 13th in the conference, have lost three in a row. The Rebels (7-1, 4-1 SEC), who are tied for third in the league, are 5-0 on their home field in 2025.

Kickoff from Vaught-Hemingway Stadium in Oxford, Miss., is at 7 p.m. ET. The Rebels are 12.5-point favorites in the latest South Carolina vs. Ole Miss odds, while the over/under for total points scored is 55.5 via SportsLine consensus. Before making any Ole Miss vs. South Carolina picks, check out the college football predictions from the Sports

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