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Chiefs will be without a major offensive weapon against Buffalo

The Kansas City Chiefs are looking to right the ship after a rocky stretch in the 2025 schedule, as they travel to Buffalo to take on the Bills . However, KC will be without one of the main cogs in their offensive machine.

Running back Isiah Pacheco, the team's leading runner with 78 carries for 329 yards and one rushing touchdown, has been ruled out due to a knee injury. The 26-year-old speedster was knocked out in the fourth quarter of the team's 28-7 win over the Washington Commanders last week.

Pacheco was injured by a tackle from Commanders cornerback Trey Amos, resulting in a sprain of the medial collateral ligament in his right knee.

A social media post by CBS Sports' Wolfson helped cle

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