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The 2025-26 men’s college basketball season tips off in earnest Monday night with 100 games on the slate. Every team across the country is hoping to cut down the nets in April of 2026, but only one team can do it.

The AP Top 25 rankings have some familiar teams at the top. Purdue is the top team in the AP poll and the Coaches Poll, followed by Houston, Florida, and Connecticut.

The betting odds aren’t exactly aligned with the polls, though. The sportsbooks have some teams a bit higher and lower than the preseason rankings. Here’s a look at the 10 teams with the best betting odds to win the national championship in 2026.

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