A 21-year-old man has been charged with murder after allegedly running over a man in Timber Creek on Monday night, amid a massive brawl in the community that also saw two other people stabbed and taken to hospital.

The mayhem occurred around 8:50pm Monday night, when police received reports that a large group of people were fighting along the Victoria Highway in Timber Creek, about 600km southwest of Darwin.

During the melee, a man started driving a vehicle dangerously through the area before striking and killing a 27-year-old male, police said.

Two others, including a 16-year-old boy and a 65-year-old woman, were reportedly stabbed during the incident.

“Investigations remain ongoing into the circumstances of the related stabbings during the incident,” police media director Mark Wilton

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