Jordan Love of the Green Bay Packers and Jalen Hurts of the Philadelphia Eagles

The second half of the 2025 NFL season kicks off Thursday when the Denver Broncos host the Las Vegas Raiders to ring in Week 10. Can't, uh, wait for that one.

However the penultimate installment of this year's International Series carries unexpected appeal, the (presently) top-seeded Indianapolis Colts and Atlanta Falcons meeting for the league's first-ever regular-season game in Berlin in what could be recently acquired CB Sauce Gardner's first game with Indy. Sunday's lower-key game of the day might actually be a showdown of first-place teams when the Tampa Bay Buccaneers come off their bye to welcome the New England Patriots. "Sunday Night Football" will pair the Pittsburgh Steelers and Chargers in Los Angeles.

But the most appealing and high-profile contest of Week 10 seems like Monday night's matchup between the Philadelphia Eagles and Green Bay Packers from Lambeau Field in another "Love Hurts" fixture that could be an NFC championship game preview. It will be the clubs' third meeting since the start of the 2024 season, the Pack unable to notch a W in the first two − one in Brazil, the other a playoff loss at Philly.

Here's how USA TODAY Sports' panel of NFL experts forecasts the rundown:

(Odds provided by BetMGM)

NFL Week 10 picks, predictions odds

  • Raiders at Broncos
  • Falcons at Colts
  • Bills at Dolphins
  • Giants at Bears
  • Saints at Panthers
  • Browns at Jets
  • Jaguars at Texans
  • Patriots at Buccaneers
  • Ravens at Vikings
  • Cardinals at Seahawks
  • Lions at Commanders
  • Rams at 49ers
  • Steelers at Chargers
  • Eagles at Packers

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This article originally appeared on USA TODAY: NFL Week 10 picks straight up and against spread: Eagles or Packers on Monday night?

Reporting by Nate Davis, USA TODAY / USA TODAY

USA TODAY Network via Reuters Connect