The Ohio State Buckeyes (8-0, 5-0 Big Ten) and the Purdue Boilermakers (2-7, 0-6) meet Saturday at Ross-Ade Stadium in West Lafayette, Indiana. Kickoff is scheduled for 1 p.m. ET (Big Ten Network). Let's analyze BetMGM Sportsbook's NCAA football odds around the Ohio State vs. Purdue odds and make our expert college football picks and predictions for the best bets.

No. 1 Ohio State leads the all-time series 42-15-2 with 1 vacated win in 2010. Last season, Ohio State won 45-0 in Columbus Nov. 9, 2024, as a 37-point favorite as the Under (56) cashed. The Buckeyes have averaged 48.3 points per game in the past 3 meetings, while allowing just 7 points in the past 2 victories. Ohio State has covered the past 3 games, while going 4-0 ATS in the past 4 matchups since October 2010 wh

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