ANZ's bottom line has taken a big hit from a massive fine imposed by the market regulator and one-off costs related to 3500 staff redundancies.

The big four bank's full-year statutory profit for the year to September 30 was down 10 per cent to $5.89 billion, and its cash profit fell 14 per cent to $5.8 billion, ANZ announced on Monday.

ANZ flagged recently that its profit would be impacted by $1.1 billion in significant items, including a $240 million fine from the market regulator for financial misconduct and a $414 million charge related to 3500 redundancies.

"While our financial performance held steady when excluding these items, our performance as a business reinforces the importance of our ANZ 2030 strategy," chief executive Nuno Matos said, referring to his plan to reset the bank.

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