World-First Trial Of At-Home LSD Microdosing Treatment For Major Depressive Disorder Produces 60 Percent Improvement In Symptoms

For the first time ever, scientists have monitored the effects of microdosing with LSD at home as a treatment for major depressive disorder. Over the course of eight weeks, 19 people took regular tiny amounts of the psychedelic drug, resulting in a pronounced reduction in symptom severity that persisted for up to six months. The rest of this article is behind a paywall. Please sign in or subscribe to access the full content.

Over the past decade or so, numerous studies have highlighted the potential of psychedelic compounds like psilocybin to combat depression, though the exact mechanisms behind this effect are still being investigated. Recent years have also seen an explosion of interest in psychedelic microdosing , which involves taking tiny, “sub-perceptual” doses of mind-altering