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Jimmy Kimmel’s longtime friend and bandleader Cleto Escobedo III has died at 59.

The two grew up together in Las Vegas and worked on "Jimmy Kimmel Live!" since 2003.

Escobedo was a noted saxophonist and is survived by his wife and two children.

Late-night talk show host Jimmy Kimmel is grieving the loss of one of his dearest and longest-time friends, Cleto Escobedo III, the bandleader of his show.

Kimmel announced Escobedo's death Tuesday on Instagram , saying "that we are heartbroken is an understatement." Escobedo was 59.

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News of Escobedo’s death comes after Thursday's episode of "Jimmy Kimmel Live!" was abruptly canceled. David Duchovny, Joe Keery and Madison Beer were set as the show’s guests. The date and cause of Escobedo's death weren't immedia

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