Tupelo Police Issue Public Safety Advisory Amid Rise in Fentanyl Activity

The Tupelo Police Department is asking residents to stay vigilant following a recent uptick in fentanyl-related activity across North Mississippi.

Law enforcement agencies report increases in both the purity and potency of fentanyl seized, particularly in areas tied to the Memphis drug supply line—trends that often spill into the Tupelo area.

In recent weeks, Tupelo has seen a noticeable rise in overdoses, surpassing levels reported in some neighboring counties. Investigators believe a particularly dangerous batch of fentanyl may be circulating locally.

Police are asking parents and guardians to speak with children and loved ones about the risks of fentanyl and counterfeit pills. Officers warn that illicit tablets are increasingly pressed to resemble legitimate prescriptions—such as oxy