Despite the 49ers’ rough 42-26 loss to the Los Angeles Rams on Sunday at Levi’s Stadium, coach Kyle Shanahan is confident in San Francisco’s ability to respond.

The 45-year-old explained how his 6-4 team is eager to get back to work -- not just because it's coming off a defeat, but because that’s the standard in the building -- to reporters at 49ers practice on Wednesday in Santa Clara.

“Yeah, I think our guys are pretty locked in every week,” Shanahan said. “Human nature [is] always something I've watched my whole career; you know, when you watch teams lose and their backs are against the wall, you see on film usually a more desperate team the next week. That's something I've seen forever, and that's something we talk about all the time.

“I think our guys, I think we get their best

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