The San Francisco 49ers lost their first NFC West game in Week 10 but will look to avoid back-to-back divisional losses with a trip to the desert to take on the Arizona Cardinals on Sunday.

When these two faced back in Week 3, it was 49ers’ backup quarterback Mac Jones outlasting the Cardinals’ starting quarterback Kyler Murray in a 16-15 San Francisco victory. The roles will be reversed as Brock Purdy will make his first start since Week 4 against Jacoby Brissett, who will be making his fifth start since replacing the injured Murray.

While Brissett has lifted Arizona’s offense, he’ll be without two weapons as he navigates the 49ers’ defense. That’s where we start this week’s numbers to know:

No targets for Jacoby Brissett

Arizona will be without 26.3 percent of its targets with Marvin

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