Few TV genres lean on memorable antagonists quite like sci-fi . From the earliest small-screen triumphs of the 20th century to the blockbuster-budgeted juggernauts of the 2020s, science fiction has always thrived on the presence of a compelling threat. When sci-fi TV soars, it’s usually because a dangerous, unforgettable figure is driving the narrative into darker, more ambitious territory.

While countless successful sci-fi shows boast at least one decent bad guy, only a select few deliver the kind of adversaries who define eras of genre storytelling. These are the series that craft foes so distinctive, so creatively realized, and so thematically resonant that they become inseparable from the shows themselves - and, in some cases, reshape the entire landscape of sci-fi villainy.

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