Katie hears voices and has been sectioned 50 times. Isiah became paranoid and tried to kill himself. Both link their illness to cannabis – and the drug is getting more and more potent. Is a tiny London clinic showing the way forward?

It’s two years since Isiah found himself on the roof of a south London shopping centre, about to jump. “I was very done,” he says of that night in November 2023. “It felt there was no other route or option. First, I did a walk around everywhere important to me: primary school, secondary, college.” Then he headed to Lewisham shopping centre. “I remember my head was telling me: ‘You’re probably better off doing this.’”

He was exhausted by his paranoia, which had grown in tandem with a cannabis habit. Now 29, he first tried marijuana at 14, becoming a daily use

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