Mutations in a gene linked to Crohn's disease deprive vital immune cells of their capacity to change modes, which leads to overreaction and inflammation , a recent study has found, per ScienceAlert. Although prior research connected variations in the NOD2 gene to Crohn's disease , its precise function in the pathophysiology of the condition had long been unknown.

Researchers use AI to understand macrophages and the gut

Researchers from the University of California, San Diego, employed machine learning techniques to find trends in the gene activity of immune cells in the gut.

By monitoring the expression of the genes of immune cells known as macrophages, the researchers were able to identify which cells maintained gut health and which developed inflammation and caused harm.

"The g

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