Key Takeaways

The diabetes drug metformin can help kids manage weight gain associated with bipolar drugs

Children taking metformin were more likely to minimize or avoid weight gain while on second-generation antipsychotics

Recent guideline changes also recommend metformin, researchers noted

MONDAY, Nov. 17, 2025 (HealthDay News) — A diabetes drug can help manage weight gain among children prescribed medications to treat bipolar disorder, a new study shows.

Second-generation antipsychotics like aripiprazole , risperidone and quetiapine are often effective in treating mood disorder, but they also can lead to substantial weight gain, researchers said.

But the diabetes drug metformin helped kids manage this weight gain, researchers report in the December issue of The Lancet Psy

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