Is Joe Mixon out for the season? When is Joe Mixon coming back? The latest Joe Mixon injury update and fantasy football outlook heading into Week 12 of 2025.

Houston Texans starting running back Joe Mixon (foot) has yet to take the field this season due to an offseason injury and is trending towards missing the remainder of the season.

With the second half well underway and him making little progress, he faces a significant uphill battle to return to action this season.

Will Mixon play again this season? Should fantasy managers stash him on their bench during the second half? Let's dive in! Be sure to check all of our fantasy football rankings for 2025:

2025 fantasy football rankings

Running back (RB) fantasy football rankings

Wide receiver (WR) fantasy football rankings

Tight

See Full Page