There are several games with College Football Playoff implications in Week 13, but perhaps none are bigger for both squads that Oregon vs. USC on CBS and Paramount+ . It likely serves as an elimination game for the two-loss Trojans, while a loss for Oregon would give the Ducks two, and likely have them more on the bubble come selection time. The latest Week 13 college football odds list the Ducks as 9.5-point home favorites.

Other Week 13 college football lines of note include Oklahoma (-9.5) vs. Missouri, Utah (-16.5) vs. Kansas State and Tennessee (-3.5) vs. Florida. Before locking in any Week 13 college football picks on those games or others, be sure to see the college football betting guide from legendary Vegas handicapper Bruce Marshall .

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