FOXBORO — Two Patriots rookies have big shoes to fill for the next four games.

Patriots free-agent-prize defensive tackle Milton Williams was placed on injured reserve Saturday with a high ankle sprain. He must miss a minimum of four games, meaning he won’t be able to return until Week 17 at the earliest.

The Patriots play the Bengals, Giants, Bills and Ravens in that timespan. They also have their bye in Week 14.

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Fortunatley, the Patriots have proven to have solid depth at defensive tackle behind Williams and fellow starter Christian Barmore. Khyiris Tonga has been one of the Patriots’ biggest steals in free agency, and Cory Durden has emerged as a valuable role player since being added in August after roster cuts.

The Patriots also have two rookies, Joshua Farmer an

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