The affected trials most often focused on infectious, respiratory and cardiovascular diseases.

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More than 380 clinical trials and tens of thousands of participants were disrupted by cuts to grant funding from the National Institutes of Health this year, according to a research analysis published Monday by JAMA Internal Medicine.

The authors examined 11,008 clinical trials funded between Feb. 28 and Aug. 15 by active NIH grants and found that 383 of them—or 3.5 percent—had lost grant funding by Aug. 15. About 36 percent of those trials were completed, 34 percent were recruiting participants, 13.7 percent were not yet recruiting participants and 11 percent were active and no longer recruiting. That last group consisted of 43 trials that enrolled 74,311 participants c

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