A trader works on the floor at the New York Stock Exchange (NYSE) in New York City, U.S., November 14, 2025. REUTERS/Jeenah Moon

(Reuters) -Wall Street's main indexes fell at the open on Tuesday, as concerns over lofty equity valuations and dimming chances of an interest rate cut from the Federal Reserve weighed on sentiment, while investors look ahead to Nvidia's earnings and key government data due later this week.

The Dow Jones Industrial Average fell 207.3 points, or 0.44%, at the open to 46382.92. The S&P 500 fell 31.2 points, or 0.47%, at the open to 6641.19, while the Nasdaq Composite dropped 142.2 points, or 0.63%, to 22565.905 at the opening bell.

(Reporting by Shashwat Chauhan in Bengaluru; Editing by Krishna Chandra Eluri)