ASIC accused ANZ of mishandling a bond sale and misconduct against thousands of retail customers. Photo: Esther Linder/AAP PHOTOS

ANZ chief executive Nuno Matos will be grilled by a parliamentary committee as the bank faces a record $240 million penalty for widespread misconduct.

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The corporate regulator has accused ANZ of mishandling a bond sale, potentially costing the federal government $26 million, as well as misconduct against nearly 65,000 retail customers.

The bank has agreed to cop the penalty - the largest ever imposed on a single entity by the regulator - which the Federal

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