The Bills (7-3) are back on Thursday Night Football for the second time in the 2025 season. On Nov. 20, they go head-to-head with the Houston Texans (5-5) with kickoff slated for 8:15 p.m. ET on Prime Video.

In 2024, Buffalo visited Houston on the road and lost 23-20. The Texans kicked a last-second field goal and came away with the walk-off win. Prior to their most recent meeting, Buffalo shutout Houston 40-0 at Highmark Stadium. The last time the Bills beat the Texans on the road was 2006.

Heading into Thursday night, both teams are coming off Week 11 wins. Buffalo beat Tampa Bay 44-32 while Houston scraped out a 16-13 win over Tennessee. Head coach Sean McDermott emphasized to his locker room after the game that whichever team has the freshest legs in the quick turnaround will be the

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