When is Marvin Harrison Jr. coming back? Will Marvin Harrison Jr. play again this season? Read about Marvin Harrison Jr.'s return date and injury updates for 2025 as of Week 12.

Arizona Cardinals wide receiver Marvin Harrison Jr. (appendicitis) missed his first game of the 2025 NFL season in a surprising turn of events due to appendicitis.

Harrison looked to be having a career resurgence after a disappointing start to his NFL journey thanks to quarterback Jacoby Brissett outperforming QB Kyler Murray (foot).

But his production this season will now (obviously) take a hit, as he's not able to play. That said, when will he return? And what's his fantasy football outlook when he's back? Let's dive in. Be sure to check all of our fantasy football rankings for 2025:

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