Blue-blood programs clash when the 24th-ranked Kansas Jayhawks battle the fifth-ranked Duke Blue Devils at the 2025 Champions Classic on Tuesday night. Kansas is coming off a 76-57 win over Princeton on Saturday, while Duke downed Indiana State 100-62 on Friday. The Jayhawks (3-1), who have won two in a row, are 0-1 against ranked opponents this season. The Blue Devils (4-0), who are 3-0 on neutral courts, are 8-6 in the Champions Classic all-time.

Tipoff from Madison Square Garden in New York is set for 9 p.m. ET. The Blue Devils are 10.5-point favorite in the latest Kansas vs. Duke odds, while the over/under for total points scored is 148.5, down two points from the opening line. Before making any Duke vs. Kansas picks, check out the men's college basketball predictions and bettin

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