New research from investigators at Florida Atlantic University (FAU) has found that a protein released by muscle during exercise can preserve memory in a mouse model of Alzheimer’s disease . The research, published in Aging Cell , details the role of Cathepsin B (Ctsb) in AD, which previously has been researched for its role in cancer, brain injury, and its associated role in cognition.

“Our study is the first to show that expressing Cathepsin B specifically in muscle can prevent memory loss and maintain brain function in a mouse model of Alzheimer’s disease,” said senior author Henriette van Praag, PhD, associate professor of biomedical science at the Charles E. Schmidt College of Medicine, Florida Atlantic University.

Ctsb is known to act as a myokine released during physical act

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