A study published in BMC Endocrine Disorders investigated the relationship between estimated glucose disposal rate (eGDR) and testosterone levels in adults with type 2 diabetes mellitus (T2DM). Researchers found that higher eGDR, a marker of improved insulin sensitivity, was linked to higher serum testosterone concentrations and a lower likelihood of testosterone deficiency. These findings suggest that metabolic health plays a significant role in regulating endocrine function in men with T2DM.

The study included adult participants with well-characterized T2DM, evaluating eGDR using standard clinical parameters and assessing serum testosterone levels. Participants with higher eGDR consistently exhibited greater testosterone levels and were less likely to meet criteria for testosterone de

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