The Carolina Panthers (6-5) and San Francisco 49ers (7-4) meet for Monday Night Football in Week 12. Kickoff from Levi's Stadium in Santa Clara, California, is scheduled for 8:15 p.m. ET (ESPN). Let's analyze BetMGM Sportsbook's NFL odds around the Panthers vs. 49ers odds and make our expert NFL picks and predictions for the best bets.

The Panthers lead the all-time series 13-10, although the 49ers have won the 2 most recent meetings. San Francisco won 37-15 in Carolina on Oct. 9, 2022, and the 49ers routed the Panthers 51-13 on Oct. 27, 2019, in the most recent meeting in the Bay Area. Carolina's last win in the series was a 23-3 win with QB Cam Newton back in 2017. RB Christian McCaffrey ran for 47 yards with 5 grabs for 38 yards as a member of the Panthers in his first-

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