The Panthers have won and covered their last three road games. But sharp bettors expect that streak to end on “Monday Night Football” against the 49ers.

San Francisco is a consensus 7½-point home favorite over Carolina after the line opened at 6½.

“The public and the sharp action is clearly on the 49ers,” Red Rock Resort sportsbook director Chuck Esposito said. “We’re going to be huge Panthers fans.”

The line is 7 at Circa Sports and the consensus total is 49½.

The Panthers are tied with the Buccaneers for first place in the NFC South division at 6-5.

The Niners, on a 3-0 over run, are in third place in the NFC West at 7-4 behind the Rams (9-2) and Seahawks (8-3) and in contention for a wild-card playoff berth.

“It’s a game the 49ers really need to win to hold on to a wild-card berth

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