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The Carolina Panthers will face the San Francisco 49ers for Monday Night Football.

The Week 12 game is scheduled for Monday, Nov. 24, 2025, at 8:15 p.m.

Viewers can watch the game on ESPN or stream it on ESPN+ and NFL+.

The San Francisco 49ers currently hold a 7-4 record for the season.

The Carolina Panthers enter the game with a season record of 6-5.

The Carolina Panthers battle the San Francisco 49ers at Levi's Stadium for Monday Night Football as the 2025 NFL season continues tonight on ESPN .

Here's what to know about how to watch the 49ers vs. the Panthers , tonight's matchup , the NFL Week 12 schedule , how to watch Monday Night Football , the Week 13 TV lineup and more.

What time does Monday Night Football San Francisco 49e

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