Teams on the fringe of the NFC playoffs will wrap up Week 12 as the San Francisco 49ers host the Carolina Panthers on 'Monday Night Football' at 8:15 p.m. ET. The over/under in this matchup is 49.5, up two points from the opening line. San Fran's offense runs through former Panthers standout Christian McCaffrey as daily Fantasy managers always have him top-of-mind when making NFL DFS picks. But the Niners also have the No. 2 passing offense, which makes Brock Purdy, Ricky Pearsall and George Kittle, all back in the lineup after recent injuries, desirable for NFL DFS lineups, despite their injury-plagued seasons. As for Carolina, its top-10 rushing attack makes the backfield tandem of Rico Dowdle and Chuba Hubbard an intriguing MNF DFS stack.

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