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NFL picks, predictions for Week 13: Texans upset Colts, 49ers shut down Shedeur Sanders-led Browns

The Indianapolis Colts have not won the AFC South since 2014.

The Colts (8-3) have been one of the surprise teams in the NFL this season – but road losses to the Steelers in Week 9 and Chiefs in Week 12 have led to questions about their true value this season.

That could be answered Sunday against the Houston Texans — the team that has won the last two AFC South division titles. Houston (6-5) has the opportunity to climb back into the division race and win for a fourth straight season at Lucas Oil Stadium. Those last three games have been decided by a combined total of seven points, but the stage is set for one of those games that could define the stretch ru

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