The Iowa State Cyclones (5-0) and Creighton Bluejays (3-2) tangle Tuesday in Day 2 of the Players Era Festival in Las Vegas, Nevada. The game at Michelob Ultra Arena will tip off at 2 p.m. ET (truTV). Let's analyze BetMGM Sportsbook's NCAA basketball odds around the Iowa State vs. Creighton odds and make our expert college basketball picks and predictions for the best bets.

No. 13 Iowa State opened its participation in the 18-team, 3-day tournament Monday vs. the St. John's Red Storm. The -2.5 Cyclones defeated SJU 83-82 (Over 159). F Milan Momcilovic went 5-of-9 from 3-point range and had 23 points to lead ISU.

Creighton played the Baylor Bears Monday. The 3.5-point-underdog Bluejays lost 81-74 (Over 154.5). Creighton was a minus-15 on the boards.

The teams have met jus

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