President Donald Trump ’s One Big Beautiful Bill Act is expected to cut hundreds of millions of dollars annually from San Francisco ’s budget, with up to 50,000 people potentially losing access to public benefits.

That’s according to a new report from the San Francisco Department of Public Health and Human Services, which estimates the federal budget could cost the city up to $400 million annually once fully implemented in 2038.

“Our economy is recovering, and we made real progress eliminating hundreds of millions of dollars every year from our structural deficit,” Mayor Daniel Lurie said in a statement. “But these changes at the state and federal level represent a real threat to San Francisco, to our residents and to our budget.”

Signed into law on July 4, the Big Beautiful Bill, a

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