Thanksgiving is synonymous with football , and there are countless NFL moments that are synonymous with the holiday.

Whether it’s stars shining under the national spotlight or bloopers fans will never forget, there have been some iconic performances on Turkey Day.

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With three games on tap for the holiday in 2025, let’s look back at some of the top Thanksgiving moments in NFL history.

O.J. Simpson made NFL history on Thanksgiving in 1976, rushing for a record 273 yards on 29 carries. To this day, it is the sixth-most rushing yards for a player in any NFL game.

Despite adding two touchdowns, Simpson's Buffalo Bills lost to the Detroit Lions 27-14.

The Chicago Bears had a Thanksgiving rally of their own in 1

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